Tris (Hydroxymethyl) Aminomethane

ürün Kodu : 108386.1000

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Ürün Grubu : Merck Kimyasalları

Var

 108386.1000

Tris(hydroxymethyl)aminomethane 

Ürün bilgisi
Grade Ph Eur,BP,USP
Synonyms Trometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer
Hill Formula C4H11NO3
Chemical formula H2NC(CH2OH)3
HS Code 2922 19 85
EC number 201-064-4
Molar mass 121.14 g/mol
CAS number 77-86-1
Kimyasal ve fiziksel veri
Solubility 800 g/l (20 °C)
Melting point 168 - 172 °C
Molar mass 121.14 g/mol
Density 1.353 g/cm3 (23 °C)
Bulk density 840 kg/m3
pH value 10.2 - 10.6 (6 g/l, H2O, 20 °C)
Boiling point 219 - 220 °C (13.3 hPa)
GHS'e göre güvenlik bilgisi
Hazard Statement(s) H315: Causes skin irritation.
H319: Causes serious eye irritation.
Precautionary Statement(s) P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Signal Word Warning
Hazard Pictogram(s)
RTECS TY2900000
Storage class 10 - 13 Other liquids and solids
WGK WGK 2 water endangering
Disposal 3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Güvenlik bilgisi
R Phrase R 36/38
Irritating to eyes and skin.
Categories of danger irritant
Hazard Symbol
Irritant
Toksikolojik veri
LD 50 oral LD50 rat 5900 mg/kg
Spesifikasyonlar
Assay
- Ph.Eur., calculated on dried substance

99.0 - 100.5 %
- USP, calculated on dried substance 99.0 - 101.0 %
Identity conforms
Appearance of solution (5 %; water) conforms
pH-value
- 1 %; water

10.3 - 10.7
- 5 %; water 10.0 - 11.5
Melting range
- lower value

≥ 168 °C
- upper value ≤ 172 °C
Chloride (Cl) ≤ 0.001 %
Sulphate (SO4) ≤ 0.005 %
Heavy metals (as Pb) ≤ 0.0010 %
As (Arsenic) ≤ 0.00002 %
Fe (Iron) ≤ 0.0010 %
Residual solvents class 3 (Ph.Eur./USP/ICH) ≤ 0.5 %
Other residual solvents (Ph.Eur./USP/ICH) excluded by production process
Related substances (TLC) ≤ 1.0 %
Sulfated ash ≤ 0.1 %
Loss on drying (105 °C) ≤ 0.5 %
Filter sample (0,45 µm) conforms
Endotoxins < 0.03 I.U./mg
Microbiological purity
- Total aerobic microbial count (TAMC)

≤ 1E+02 CFU/g
- Total yeast and mould count (TYMC) ≤ 1E+02 CFU/g
 
- Bile tolerant Gram negative Bacteria (absent in 1 g)

conforms
- Escherichia coli (absent in 1 g) conforms
- Pseudomonas aeruginosa (absent in 1 g) conforms
- Staphylococcus aureus (absent in 1 g) conforms
- Candida albicans (absent in 1 g) conforms
- Salmonella ssp (absent in 10 g) conforms
Corresponds to Ph Eur, BP, USP
Tris(hydroxymethyl)aminomethane, molecular structure